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DSPE-PEG2000 ,MPEG2000-DSPE, 147867-65-0

商品型号:PS1-DE-2K

英文简称:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)2000]

分子量:2805.497 (average MW due to polydispersity of PEG)

规格:0.5g,1g,5g

提示:In stock
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DSPE-PEG2000 MPEG2000-DSPE 147867-65-0

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethyleneglycol)2000]

Synonym: MethoxyPolyethylene Glycol DSPE2000 MethoxyPEG2000 DSPE, mPEG2000 DSPE, PEG2000DSPE, DSPE-MPEG2000.

ProductStructure:



ProductSpecifications:

l CatalogNumbers:PS1-DE-2K.

l Appearance: Whiteto off-white solid.

l Solubility: >10mg/mL in warm water, chloroform, DCM, methanol.

l Stability: 2 Years at-20°C, Desiccate.

l CASNumber: 147867-65-0,474922-77-5,

l MolecularWeight: 2805.497 (average MW due to polydispersity ofPEG).

l Purity: 95%.


Description:

Methoxypolyethyleneglycol DSPE (mPEG-DSPE) is one of Ponsure phospholipid PEGderivatives that has a terminal DSPE group on PEG end. DSPE(1,2-distearoyl-sn-glycero-3-phospho-ethanolamine) is a C18 saturatedphospholipid with high hydrophobicity. Pegylated DSPE demonstrates excellentamphilphilic properties and offer superior advantages for small and largemolecule encapsulation and delivery. Our DSPE PEG has been used for liposomedrug formulation, cell membrane study and many other studies. Besides our monofunctionalPEG lipids.


Handlingand Use:

DSPEPEG(MPEG-DSPE) should always be kept in low temperature in drycondition. Prepare fresh solution right before use.Avoid frequent thaw andfreezing. For more information about using this product,  visit www.ponsure.com.


RelatedProducts:

DSPE-PEG-NH2,DSPE-PEG-COOH

DSPE-PEG-NHS,DSPE-PEG-FA

DSPE-PEG-SH,DSPE-PEG-MAL


References

l Ultrafastand Non-invasive Long-Term Bioimaging with Highly Stable RedAggregation-Induced Emission Nanoparticles------ AnalyticalChemistryIF=6.042

l Ultra-smallnanocluster mediated synthesis of Nd 3+ -doped core-shellnanocrystals with emission in the second near-infrared window for multimodalimaging of tumor vasculature------ Biomaterials(IF=10.273)

l Novelsmall molecular dye-loaded lipid nanoparticles with efficient near-infrared-IIabsorption for photoacoustic imaging and photothermal therapy of hepatocellularcarcinoma------ Biomaterials(IF=10.273)

l HybridNanoclusters for Near-Infrared to Near-Infrared Upconverted PersistentLuminescence Bioimaging------ Acs applied  materials&interfaces(IF=8.097)

l HierarchicallyTheranostic Nanomedicine: MRI Contrast Agents as the Physical Vehicle Anchorfor High Drug Loading and Triggered on-demand Delivery------ Journalof Materials Chemistry B(IF=4.776)

l DualNear-Infrared Emissive Luminescent Nanoprobe for Ratiometric LuminescentMonitoring of ClO-in Living Organisms------ Acs applied  materials&interfaces(IF=8.097)

l Near-InfraredUpconversion Luminescence and Bioimaging In Vivo Based on Quantum Dots------ Advancedscience(IF=12.441)

l Afatinib-loadedImmunoliposomes Functionalized with Cetuximab: a Novel Strategy Targeting theEpidermal Growth Factor Receptor for Treatment of Non-small-cell Lung Cancer------ InternationalJournal of Pharmaceutics(IF=3.862)

l Zincphthalocyanine-soybean phospholipid complex based drug carrier for switchablephotoacoustic/fluorescence image, multiphase photothermal/photodynamictreatment and synergetic therapy------Journal of Controlled Release(IF=7.877)

l Mitoxantrone-preloadedwater-responsive phospholipid-amorphous calcium carbonate hybrid nanoparticlesfor targeted and effective cancer therapy------ InternationalJournal of Nanomedicine(IF=4.37)

l Ultralong  Circulating Choline  Phosphate Liposomal  Nanomedicines for  Cascaded Chemo-Radiotherapy------ BiomaterialsScience(IF=5.831)

l Nano-biotinylatedliposome-based immunoassay for the ultrasensitive detection of proteinbiomarker in urine------ Talanta(IF=4.244)

l In vitroand in vivo evaluation of folate mediated PEGylated nanostructured lipidcarriers for the efficient delivery of furanodiene.

l MultifunctionalNanoparticles Enable Efficient Oral Delivery of Biomacromolecules via ImprovingPayload Stability and Regulating the Transcytosis Pathway------Acs applied  materials&interfaces(IF=8.097)

l Light/magnetichyperthermia triggered drug released from multi-functional thermo-sensitivemagnetoliposomes for precise cancer synergetic theranostics------Journal ofControlled Release(IF=7.877)

l Noveltheranostic zinc phthalocyanine–phospholipid complex self-assembled  nanoparticles for  imaging-guided  targeted photodynamic treatment withcontrollable ROS production and shape-assisted enhanced cellular uptake------ Colloidsand Surfaces B: Biointerfaces(IF=3.997)

l Erythrocytemembrane camouflaged graphene oxide for tumor-targetedphotothermal-chemotherapy------ Carbon(IF=7.082)



Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.

Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
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